Nucleotide regions with various extents of
flexibility in tRNA Phe,
shown in red, orange, yellow, green and blue, in order of increasing mobility
in the global conformational motion, presented in (a) cover-leaf representation,
and (b) ribbon diagram. The nucleotides shown in red, are almost rigid in the slowest(global) mode of motion of folded tRNAPhe,
and therefore may be viewed as forming the hinge region of the molecule. At
other extreme, nucleotides exhibiting the largest amplitude motions, shown in
blue, we onserve those in the anticodon
loop and the CCA sequence at the amino acis acceptor
end. Note that base 59 should be red and 62 should be orange.
"Vibrational
dynamics of transfer RNAs. Comparison of the free and enzyme-bound forms"
I. Bahar, R. L. Jernigan, J. Mol. Biol. 281, 871-884, 1998